Academic Journals Database
Disseminating quality controlled scientific knowledge

Entrainment of the circadian clock in humans: mechanism and implications for sleep disorders.

Author(s): David Metcalfe

Journal: Impulse : an Undergraduate Journal for Neuroscience
ISSN 1934-3361

Start page: 1;
Date: 2007;
VIEW PDF   PDF DOWNLOAD PDF   Download PDF Original page

Keywords: Circadian rhythm | sleep disorders | sleep phase syndrome | dyssomnia | jet lag syndrome

Humans exhibit behaviour and physiology controlled by a circadian clock. The circadian period is genetically determined and administered by a series of interlocked autoregulatory feedback loops largely in the suprachiasmatic nuclei of the hypothalamus. The phase of the clock is, however, synchronised by a number of external environmental cues such as light. A failure or change in any one of the requisite clock components may result in the onset of a long-term sleep disorder. This review discusses the mechanism regulating circadian physiology in humans and explores how disturbances of this mechanism may result in sleep pathologies.
RPA Switzerland

RPA Switzerland

Robotic process automation


HR software für Hotellerie

Automatische Erstellung
von Personaldokumente
und Anmeldungen bei Behörden