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Evaluation of In Vitro Free Radical Scavenging Efficacy of Aerial Parts of Medicinally Important Morinda pubescens J.E. Smith (Morinda tinctoria Roxb.)

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Author(s): Kolli Deepti | Parimi Umadevi | Gutta Vijayalakshmi

Journal: Drug Invention Today
ISSN 0975-7619

Volume: 3;
Issue: 6;
Start page: 72;
Date: 2011;
Original page

Keywords: Morinda tinctoria | free radical scavenging activity | DPPH

ABSTRACT
The present study evaluated the anti-oxidant efficacy of methanolic, chloroform and ethyl acetate extracts of Morinda tinctoria aerial parts using catechin as a standard antioxidant. The free radical scavenging activity of the extracts was evaluated according to the procedure described by Nickavar et al. (2006) [1] using 1, 1-diphenyl-2-picrylhydrazyl (DPPH). The methanolic extract of M. tinctoria showed IC50 with minimum concentration of 180μg/ml and more effective in scavenging DPPH followed by ethylacetate extract and chloroform extract with concentrations of 200μg/ml and 250μg/ml respectively. The present results suggest that the extracts of M. tinctoria aerial parts have radical scavenging activity and can be recommended as potent antioxidants. The preliminary phytochemical screening of the aerial parts revealed the presence of saponins, terpenoids, tannins, flavonoids, glycosides and sugars.
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