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Evolution of Cellular Inclusions in Bietti’s Crystalline Dystrophy

Author(s): Emiko Furusato | J. Douglas Cameron | Chi-Chao Chan

Journal: Ophthalmology and Eye Diseases
ISSN 1179-1721

Volume: 2010;
Issue: 2;
Start page: 9;
Date: 2010;
Original page

Bietti’s crystalline dystrophy (BCD) consists of small, yellow-white, glistening intraretinal crystals in the posterior pole, tapetoretinal degeneration with atrophy of the retinal pigment epithelium (RPE) and “sclerosis” of the choroid; in addition, sparking yellow crystals in the superficial marginal cornea are also found in many patients. BCD is inherited as an autosomal-recessive trait (4q35-tel) and usually has its onset in the third decade of life. This review focuses on the ultrastructure of cellular crystals and lipid inclusions of BCD.
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