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Evolution of the concept of drug-related problems: outcomes as the focus / Evolución del concepto de problemas relacionados con medicamentos:resultados como el centro del nuevo paradigma

Author(s): Fernandez-Llimos F | Faus MJ | Gastelurrutia MA | Baena MI | Martinez Martinez F

Journal: Seguimiento Farmacoterapéutico
ISSN 1696-1137

Volume: 3;
Issue: 4;
Start page: 167;
Date: 2005;
Original page

Keywords: Outcome Assessment | Adverse Effects | Drug-related Problems | Medication Errors.

Objective: To review the concept of drug-related problems and drug therapy problems, and its relationship with other concepts, like medication negative outcomes.Methods: Primary articles were identified through a MEDLINE search (1966 to September 2004); reference cites from the articles found provided additional resource material. Retrieved and selected papers were reviewed and relevant information was included.Results: the term drug-related problem has been widely used in literature, not always representing a simple concept. Process (causes) and outcomes (effects) had been mixed under different DRP definitions and classifications. Drug therapy problems, medicine-related problems and medication related problems are other terms used to define the same unclear concept. The idea of actual and potential problems was created to act on preventing the effect of these problems. This paper suggests the use of commonly accepted biomedical terms, and put these concepts into recognized models and paradigms (namely, SPO and ECHO). Also the name of medication negative clinical outcomes is proposed.Conclusions: Any medication negative clinical outcome can be assigned to a single definition and classification. A Systematic identification tool has been shown to be effective in detecting each and every one of the negative clinical outcomes in patient pharmacotherapy.
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