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Exoresection and endoresection for uveal melanoma

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Author(s): Gunduz Kaan | Bechrakis Nikolaos

Journal: Middle East African Journal of Ophthalmology
ISSN 0974-9233

Volume: 17;
Issue: 3;
Start page: 210;
Date: 2010;
Original page

Keywords: Endoresection | Exoresection | Nevus | Melanoma | Partial Lamellar Sclerouvectomy

ABSTRACT
Surgical resection of uveal melanomas is an alternative eye-salvaging approach to the more commonly used irradiation techniques. There are two surgical resection techniques: Transscleral resection or "Exoresection" via a partial lamellar sclerouvectomy and "Endoresection" via a pars plana vitrectomy. While exoresection is more applicable to anteriorly located tumors with ciliary body and/or iris involvement, endoresection is more suitable for posteriorly located tumor without ciliary body involvement. Both approaches are suitable for large tumors with> 8 mm in thickness. In general, eyes containing these large tumors have a very dismal prognosis regarding long-term visual function, eye retention, and irradiation-induced side effects. By removing the tumor burden from the eye, histopathologic and cytogenetic information of the tumor is available and complications associated with the so-called toxic tumor syndrome are avoided. However, both types of surgical resection are challenging surgical procedures, bearing the risk of early and late postoperative complications.
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