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Hippocampal Physiology, Structure and Function and the Neuroscience of Schizophrenia: A Unified Account of Declarative Memory Deficits, Working Memory Deficits and Schizophrenic Symptoms

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Author(s): Cynthia G. Wible

Journal: Behavioral Sciences
ISSN 2076-328X

Volume: 3;
Issue: 2;
Start page: 298;
Date: 2013;
Original page

Keywords: hippocampus | memory | schizophrenia | parietal | superior temporal sulcus | social cognition

ABSTRACT
Memory impairment is a consistent feature of the schizophrenic syndrome. Hippocampal dysfunction has also been consistently demonstrated. This review will discuss neurophysiological and neuroanatomical aspects of memory formation and how they relate to memory impairment in schizophrenia. An understanding of the cellular physiology and connectivity of the hippocampus with other regions can also aid in understanding the relationship between schizophrenic declarative or relational memory deficits, working memory deficits and the clinical symptoms of the syndrome.
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