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Immunoglobulin changes in boars exposed to administration of levamisole and exogenous adrenocorticotropic hormone

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Author(s): Bilandžić Nina | Terzić Svjetlana | Šimić B.

Journal: Acta Veterinaria
ISSN 0567-8315

Volume: 62;
Issue: 5-6;
Start page: 495;
Date: 2012;
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Keywords: ACTH | albumins | boars | globulins | immunoglobulins | levamisole | total proteins

ABSTRACT
The objective of this paper was to determine the effect of levamisole (LEV) on immunoglobulin concentration in the serum of boars exposed to 3-day stress induced by exogenous ACTH. Boars were assigned to 4 groups (n=7). The first group received LEV for 3 days (2.5 mg/kg BW), the second group received ACTH (10 μg/kg BW) for 3 days and the third group received LEV for 3 consecutive days and ACTH for the following 3 days (2.5 mg/kg BW; ACTH 10 μg/kg BW). The control group received saline solution during the 6 days. Concentrations of cortisol, total protein, globulin, albumin and immunoglobulin (IgG, IgA and IgM) were determined during treatments and on the 16th day post-administration. Cortisol concentration was increased in both ACTH treated groups during all three days of administration and the day after the last ACTH treatment (p
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