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Innate immune modulation in EBV infection

Author(s): Ning Shunbin

Journal: Herpesviridae
ISSN 2042-4280

Volume: 2;
Issue: 1;
Start page: 1;
Date: 2011;
Original page

Abstract Epstein-Barr Virus (EBV) belongs to the gammaherpesvirus family, members of which are oncogenic. Compared with other closely related herpesviruses, EBV has developed much more elaborate and sophisticated strategies for subverting host immune system, which may account for its high prevalence in immune competent hosts. Thus, study of EBV-specific immune dysregulation is important for understanding EBV latency and oncogenesis, and will identify potential molecular targets for immunotherapeutic interventions. Here I summarize the recent findings of individual EBV products in regulating host immune responses, with emphasis on the innate immune modulation.

Tango Jona
Tangokurs Rapperswil-Jona


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