Academic Journals Database
Disseminating quality controlled scientific knowledge

Intensity-Modulated Radiation Therapy with or without Chemotherapy for Nasopharyngeal Carcinoma: A Clinical Review

Author(s): Nicola Caria | Jeremy Setton | Edward Shin | Nancy Lee

Journal: The Asia-Pacific Journal of Oncology & Hematology
ISSN 1759-6637

Volume: 2;
Issue: 1;
Start page: 95;
Date: 2010;
VIEW PDF   PDF DOWNLOAD PDF   Download PDF Original page

Keywords: intensity-modulated radiotherapy | nasopharyngeal cancer | head and neck | chemotherapy

The introduction of intensity-modulated radiation therapy (IMRT), a modern approach which permits the delivery of high doses to the primary tumor while adequately sparing the surrounding normal tissue, has led to progress in the treatment of nasopharyngeal carcinoma (NPC). This advancement in radiation oncology, combined with the introduction of concomitant chemotherapy, has resulted in impressive improvements in local–regional control. Furthermore, the advent of IMRT has reduced the incidence of severe toxicities, such as xerostomia, associated with previous radiotherapy techniques. Nevertheless, distant metastases remain a significant threat to the overall survival of patients with NPC. The present review focuses its analysis on the role of IMRT in the treatment of NPC, including a discussion of radiotherapy technique, planning issues, imaging modalities, chemotherapy, treatment outcomes, and future directions.
RPA Switzerland

Robotic Process Automation Switzerland


Tango Rapperswil
Tango Rapperswil