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The investigation of relationship between preeclampsia and antiphospholipid antibody syndrome

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Author(s): Gökhan Açmaz | Ahmet Tayyar | Gökalp Öner | Mehmet Tayyar

Journal: Cumhuriyet Medical Journal
ISSN 1305-0028

Volume: 35;
Issue: 1;
Start page: 83;
Date: 2013;
Original page

Keywords: Preeclampsia | Antiphospholipid antibodies | Pregnancy

ABSTRACT
Aim. The aim of this study was evaluate the relationship between preeclampsia and antiphospholipid antibodies. Methods. A total of 116 pregnant women between 20th and 40th weeks of gestation admitted to our department were investigated. 63 of them were allocated our preeclampsia group and 53 of them were allocated our control group. Lupus anticoagulant, anti-cardiolipin antibodies (IG G ve M) and antiphosphatidylserine antibodies (IG G ve M) were measured. Results. There was no statistical significance between preeclampsia and control group for antiphospholipid antibodies but these were two times higher in preeclamptic group compared to control group. (22.2% in preeclampsia, 11.3% in control group p=0.193). Conclusions. In an unselected population we were not able to demonstrate an association between preeclampsia and antiphospholipid antibody syndrome but antiphospholipid antibody ratio elevated in women with preeclampsia. These findings show that, there is a need for large scale studies.
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