Author(s): Iadeishisha Kharbangar | Md. Rumum Rohman | Hormi Mecadon | Bekington Myrboh
Journal: International Journal of Organic Chemistry
ISSN 2161-4687
Volume: 02;
Issue: 03;
Start page: 282;
Date: 2012;
Original page
Keywords: 4H-Pyran derivatives | Ethanol | KF-Al2O3 | Room Temperature | Three-Component
ABSTRACT
KF-Al2O3 as a recyclable basic catalyst for the three-component synthesis of 4H-pyran derivatives by the reaction of aldehydes, malononitrile and active methylene dicarbonyl compounds in ethanol at room temperature is described. The protocol is environmentally benign and offers rapid access to a wide array of 4H-pyran heterocycles in good to excellent yields.
Journal: International Journal of Organic Chemistry
ISSN 2161-4687
Volume: 02;
Issue: 03;
Start page: 282;
Date: 2012;
Original page
Keywords: 4H-Pyran derivatives | Ethanol | KF-Al2O3 | Room Temperature | Three-Component
ABSTRACT
KF-Al2O3 as a recyclable basic catalyst for the three-component synthesis of 4H-pyran derivatives by the reaction of aldehydes, malononitrile and active methylene dicarbonyl compounds in ethanol at room temperature is described. The protocol is environmentally benign and offers rapid access to a wide array of 4H-pyran heterocycles in good to excellent yields.
