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Langerhans Cell Histiocytosis (LCH) and Diabetes Insipidus with Mandibular lesion

Author(s): Sayeh Alizad jahani | Somaye Khosravi | Mohammad Reza Mohajeri Tehrani | Bgher Larijani

Journal: Electronic Physician
ISSN 2008-5842

Volume: 4;
Issue: 2;
Start page: 516;
Date: 2012;
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Keywords: Langerhans cell histicytosis (LCH) | Diabetes insipidus (DI) | Mandibular lesion

: Langerhans cell histicytosis (LCH) is a rare disorder that primarily affects children. Its occurrence inadult is very rare. We report a case of 42 year old female patient who presented polyuria and polydipsia, loosingteeth and diplopia added to symptom .The diagnostic workup revealed endocrine involvement with diabetesinsipidus. The x ray Orthopantomogram (OPG) showed destructive bone lesion of mandible. Biopsy of lesionrevealed histiocytosis X. We herein describe the case report of Langerhans cell histiocytosis on mandible andinvolvement endocrine system.
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