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Long-Term Clinical and Neurophysiological Follow-Up of Familial Amyloid Polyneuropathy Patients after Liver Transplantation: Comparison between Two Historical Different Groups of Patients

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Author(s): Isabel M Conceição | José F Castro | Mamede de Carvalho

Journal: European Neurological Journal
ISSN 2041-8000

Volume: 2;
Issue: 2;
Start page: 83;
Date: 2010;
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Keywords: electromyography | familial amyloid polyneuropathy | liver transplantation | nerve conduction studies

ABSTRACT
We tested if patients with familial amyloid polyneuropathy (FAP) type I have had a better outcome after liver transplantation (LT) in recent years. We compared two identical groups of patients: group I, 14 patients who underwent LT between 1993 and 2002; group II, 19 patients submitted to LT between 2003 and 2007. We found no statistically significant difference in clinical and neurophysiological progression between the two groups after LT; nerve function did not improve. Novel treatments are necessary.
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