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MICROWAVE ASSISTED SOLVENT-FREE SYNTHESIS OF PYRAZOLO [4,3-C] QUINOLINES USING MONTMORILLONITE K-10 CLAY: AN ENVIRONMENTAL BENIGN APPROACH Mikrowellenunterstützten LÖSEMITTELFREIE SYNTHESIS von Pyrazolo [4,3-c] Chinoline VERWENDUNG Montmorillonit K-10 CLAY: AN UMWELT Gutartige ANSATZ

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Author(s): Raja S.Bhupathi, B.RamaDevi and P.K.Dubey

Journal: Heterocyclic Letters
ISSN 2231-3087

Volume: 3;
Issue: 2;
Start page: 121;
Date: 2013;
Original page

Keywords: 4-chloro-quinoline-3-carboxylates | pyrazolo [4 | 3-c] quinolines | Gould-Jacobs reaction | K-10 clay | microwave irradiation.

ABSTRACT
A series of novel pyrazolo[4,3-c]quinolines have been synthesized in good to excellent yields by environmental benign solvent free microwave -induced technique involving condensation of ethyl-4-chloroquinoline-3-carboxylates 5 (a-d) with different hydrazines using montmorillonite K-10 clay as a catalyst. All new compounds were characterized by spectral and analytical methods.

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