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Modelling One-Pot Method for Synthesis of 2,3-Dihydro-1H-pyrrolo[2,1-c][1,4]benzothiazine 5,5-Dioxides and Their Homologues

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Author(s): Oleksandr Yu Grevtsov | Oleg V. Zaremba | Anna B. Bondarenko | Oleksandr G. Drushlyak | Sergiy M. Kovalenko | Valentyn P. Chernykh

Journal: International Journal of Organic Chemistry
ISSN 2161-4687

Volume: 03;
Issue: 02;
Start page: 125;
Date: 2013;
Original page

Keywords: Sulfones | Lactims | Cyclization | Heterocycles | Nucleophilic Aromatic Substitution

ABSTRACT
A facile method for synthesis of 2,3-dihydro-1H-pyrrolo[2,1-c][1,4]benzothiazines by interaction of methylenactive (2-fluorophenyl)sulfones with homologues of either 5-methoxy-3,4-dihydro-2H-pyrrole or 5-(methylthio)-3,4-dihydro- 2H-pyrrole has been developed.

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