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Non-invasive ventilation in acute respiratory failure in children

Author(s): Clara Abadesso | Pedro Nunes | Catarina Silvestre | Ester Matias | Helena Loureiro | Helena Almeida

Journal: Pediatric Reports
ISSN 2036-749X

Volume: 4;
Issue: 2;
Start page: e16;
Date: 2012;
Original page

Keywords: Non-invasive ventilation | acute respiratory failure | child | infant | predictive factors | pediatric intensive care unit

The aim of this paper is to assess the clinical efficacy of non-invasive ventilation (NIV) in avoiding endotracheal intubation (ETI), to demonstrate clinical and gasometric improvement and to identify predictive risk factors associated with NIV failure. An observational prospective clinical study was carried out. Included Patients with acute respiratory disease (ARD) treated with NIV, from November 2006 to January 2010 in a Pediatric Intensive Care Unit (PICU). NIV was used in 151 patients with acute respiratory failure (ARF). Patients were divided in two groups: NIV success and NIV failure, if ETI was required. Mean age was 7.2±20.3 months (median: 1 min: 0,3 max.: 156). Main diagnoses were bronchiolitis in 102 (67.5%), and pneumonia in 44 (29%) patients. There was a significant improvement in respiratory rate (RR), heart rate (HR), pH, and pCO2 at 2, 6, 12 and 24 hours after NIV onset (P
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