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Ocular surface squamous neoplasia masquerading as superior limbic keratoconjunctivitis

Author(s): Moshirfar Majid | Khalifa Yousuf | Kuo Annie | Davis Don | Mamalis Nick

Journal: Middle East African Journal of Ophthalmology
ISSN 0974-9233

Volume: 18;
Issue: 1;
Start page: 74;
Date: 2011;
Original page

Keywords: Conjunctival Intraepithelial Neoplasia | Masquerade | Ocular Surface Squamous Neoplasia | Superior Limbic Keratoconjunctivitis

To report a case of ocular surface squamous neoplasia (OSSN) masquerading as superior limbic keratoconjunctivitis (SLK). A 62-year-old woman was referred with foreign body sensation, irritation, photophobia and decreased vision in the left eye. She was initially treated for 10 months with intermittent topical corticosteroids for a presumed diagnosis of SLK. She underwent excisional biopsy of the superior conjunctiva and was found, on histopathologic evaluation, to have OSSN with moderate to marked dysplasia. This is the first reported case of OSSN masquerading with signs and symptoms of SLK. Any ocular surface lesion refractory to standard medical treatment should raise suspicion for a malignant process and warrant further cytologic or histopathologic evaluation.
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