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Optimisation of New Generation Endo-coronary Fourier Domain Optical Coherence Tomography

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Author(s): Righab Hamdan | Saiid Ghostine | Nicolas Amabile | Christiophe Caussin

Journal: European Journal of Cardiovascular Medicine
ISSN 2042-4884

Volume: 11;
Issue: 111;
Date: 2013;
Original page

Keywords: New generation endo-coronary | optical coherence tomography

ABSTRACT
Background and aim: Fourier domain Optical Coherence Tomography is a new imaging modality characterised by a high resolution (10 -15) μm. We aimed to optimise this technique by determining the optimal flushing solution, the optimal pull-back speed, and the optimal injection rate and volume regimen.Materials and methods: Animal model: We performed FD-OCT on a swine model. We tested multiple flushing solutions at 2 injection rate and volume regimens.Results: Half strength Iodixanol/ voluven solution yielded excellent image quality comparable to the full strength Iodixanol.Conclusion: Half strength Iodixanol/ voluven solution seems to be an efficient alternative to full strength Iodixanol with an acquisition quality comparable and with half the usual dose of contrast agent.

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