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Partial mole associated with the HELLP syndrome at 15 weeks of pregnancy: a case report

Author(s): Ana Amaral

Journal: Acta Obstetrica e Ginecologia Portuguesa
ISSN 1646-5830

Hydatidiform mole comprises the vast majority of gestational trophoblastic disease cases. Although noninvasive and localized, hydatidiform moles can be lifethreatening, due to the risk of complications and evolution to persistent forms. HELLP syndrome is a rare and serious condition that usually occurs after 20 weeks of pregnancy. There are only a few cases of HELLP syndrome reported in association with molar pregnancies. The authors report a case where a partial mole with fetal triploidy coexisted with a typical presentation of preeclampsia and HELLP syndrome at 15 weeks of gestation. The patient was admitted in our department with hyperemesis and preeclampsia. Ultrasound findings were consistent with partial hydatiform mole. Termination of pregnancy was performed and histophatological examination confirmed fetal triploidy and partial molar pregnancy. A few hours after abortion the patient developed HELLP syndrome, requiring intensive care unit admission, but the whole clinical picture subsequently resolved spontaneously.
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