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Phytochemical investigation of root extract of the plant Carissa spinarum

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Author(s): Karunakar Hegde, D. Satyanarayana, Arun B. Joshi

Journal: RGUHS Journal of Pharmaceutical Sciences
ISSN 2249-2208

Volume: 2;
Issue: 1;
Start page: 55;
Date: 2012;
Original page

ABSTRACT
From the petroleum ether extract of the roots of Carissa spinarum Linn. (Apocynaceae), six compounds namely stigmasterol, ursolic acid, lupeol, campesterol, 17-hydroxy-11-oxo-nor-β-amyrone and urs-12-ene-3β, 22β-diol- 17-carboxylic acid have been isolated by column chromatography. Their structures were characterized by m.p., IR, 1HNMR, 13CNMR and mass spectral data. However, the compounds stigmasterol, campesterol, 17-hydroxy- 11-oxo-nor-β-amyrone and urs-12-ene-3β, 22β-diol-17-carboxylic acid were reported for the fi rst time from the root of this plant. Keywords: Carissa spinarum, Root extract, Sterol, Triterpenoids
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