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Pilot study on multidrug resistant tuberculosis in Nigeria

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Author(s): Lawson L | Habib A | Okobi M | Idiong D | Olajide I | Emenyonu N | Onuoha N | Cuevas L | Ogiri S

Journal: Annals of African Medicine
ISSN 1596-3519

Volume: 9;
Issue: 3;
Start page: 184;
Date: 2010;
Original page

Keywords: Drug resistance | human immunodeficiency virus | prevalence | Nigeria | tuberculosis

ABSTRACT
Background: Drug resistant tuberculosis (TB) has lately emerged and it represents a serious public health problem. We set out to determine drug resistance among TB patients. Methods: Using automated BACTEC cultures, multidrug resistant-tuberculosis (MDR-TB) was investigated in 117 diagnosed cases in Abuja, Nigeria. Results: Ten (31%) of 32 culture-positive patients were resistant to at least one and four (13%) to all of the four drugs tested. No association between drug resistance and human immunodeficiency virus (HIV) infection was found. Conclusions: MDR-TB is present in Nigeria and larger studies are urgently required. TB clinical management and control efforts should be improved.
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