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Potential Anti-HIV Agents from Marine Resources: An Overview

Author(s): Thanh-Sang Vo | Se-Kwon Kim

Journal: Marine Drugs
ISSN 1660-3397

Volume: 8;
Issue: 12;
Start page: 2871;
Date: 2010;
Original page

Keywords: anti-HIV agents | AIDS | phlorotannins | marine resources

Human immunodeficiency virus (HIV) infection causes acquired immune deficiency syndrome (AIDS) and is a global public health issue. Anti-HIV therapy involving chemical drugs has improved the life quality of HIV/AIDS patients. However, emergence of HIV drug resistance, side effects and the necessity for long-term anti-HIV treatment are the main reasons for failure of anti-HIV therapy. Therefore, it is essential to isolate novel anti-HIV therapeutics from natural resources. Recently, a great deal of interest has been expressed regarding marine-derived anti-HIV agents such as phlorotannins, sulfated chitooligosaccharides, sulfated polysaccharides, lectins and bioactive peptides. This contribution presents an overview of anti-HIV therapeutics derived from marine resources and their potential application in HIV therapy.
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