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Purslane Effect on GLP-1 and GLP-1 receptor in type 2 diabetes

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Author(s): Sara Heidarzadeh | Parvin Farzanegi | Mohammad Ali Azarbayjani | Roja Daliri

Journal: Electronic Physician
ISSN 2008-5842

Volume: 5;
Issue: 1;
Start page: 582;
Date: 2013;
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Keywords: Purslane | Anti-diabetic factors | Type II diabetic women

ABSTRACT
Abstract:Background: The aim of this study was to examine the effect of purslane seeds in glucagon-like peptide-1 concentration and glucagon-like peptide-1 receptor in women with diabetes.Methods: This was a quasi-experimental study. The population was consisted of the city of Sari where diabetic women with diabetes II who had no history of using purslane seeds. All individuals used the same dose of metformin under the specialist supervision. Among these individuals, 16 were assigned at random to Purslane group and control group. The purslane group consumed 2.5 grams Purslane with lunch and along with 5 grams of purslane (Portulaca oleracea seeds 7.5 g daily) with dinner meals twice daily for 8 weeks. Blood sample was taken before and after 8 weeks, after 12 hours of fasting to 5 ml of the left brachial vein.Results: After 8 weeks using purslane seeds in the experimental group, a significant increase was seen in glucagon-like peptide-1 concentrations (p
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