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Q-Analysis Methods for the Simultaneous Spectrophotometric Estimation of Levofloxacin Hemihydrate and Ornidazole in Tablet Dosage Form

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Author(s): Rekha Rajeev Kumar | P. Rajeev Kumar

Journal: Stamford Journal of Pharmaceutical Sciences
ISSN 1999-7108

Volume: 3;
Issue: 2;
Start page: 16;
Date: 2010;
Original page

Keywords: Levofloxacin | Ornidazole | UV-spectrophotometry | Q-Analysis

ABSTRACT
Two simple, accurate and economic Q-analysis and two wavelength methods have been developed and validated for the simultaneous estimation of Levofloxacin Hemihydrate (LFH) and Ornidazole (ORN) in tablet dosage form. In 0.1M HCl AR grade the λmax were found to be 293 and 277nm, respectively. Beer’s lamberts law was obeyed in the concentration range of 2-12 µg/ml for LFH and 2-32 µg/ml for ORN. The results of analysis have been validated by statistical and recovery studies.
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