Academic Journals Database
Disseminating quality controlled scientific knowledge

Radiotherapy treatment planning: Benefits of CT-MR image registration and fusion in tumor volume delineation

Author(s): Đan Igor | Petrović Borislava | Erak Marko | Nikolić Ivan | Lučić Silvija

Journal: Vojnosanitetski Pregled
ISSN 0042-8450

Volume: 70;
Issue: 8;
Start page: 735;
Date: 2013;
VIEW PDF   PDF DOWNLOAD PDF   Download PDF Original page

Keywords: radiotherapy | radiotherapy planning | computer assisted | tomography | x-ray computed | magnetic resonance imaging

Background/Aim. Development of imaging techniques, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET), made great impact on radiotherapy treatment planning by improving the localization of target volumes. Improved localization allows better local control of tumor volumes, but also minimizes geographical misses. Mutual information is obtained by registration and fusion of images achieved manually or automatically. The aim of this study was to validate the CT-MRI image fusion method and compare delineation obtained by CT versus CT-MRI image fusion. Methods. The image fusion software (XIO CMS 4.50.0) was applied to delineate 16 patients. The patients were scanned on CT and MRI in the treatment position within an immobilization device before the initial treatment. The gross tumor volume (GTV) and clinical target volume (CTV) were delineated on CT alone and on CT+MRI images consecutively and image fusion was obtained. Results. Image fusion showed that CTV delineated on a CT image study set is mainly inadequate for treatment planning, in comparison with CTV delineated on CT-MRI fused image study set. Fusion of different modalities enables the most accurate target volume delineation. Conclusion. This study shows that registration and image fusion allows precise target localization in terms of GTV and CTV and local disease control.
RPA Switzerland

RPA Switzerland

Robotic process automation


Tango Rapperswil
Tango Rapperswil