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Relationship Of FEF25-75, PEFR And SVC With Estrogen And Progesterone Level In Postmenopausal Women

Author(s): Zinat Ara Polly | Shelina Begum, | Sultana Ferdousi | Noorzahan Begum | Taskina Ali | Afroza Begum

Journal: Journal of Bangladesh Society of Physiologist
ISSN 1995-1213

Volume: 6;
Issue: 2;
Start page: 116;
Date: 2011;
Original page

Keywords: Menopause | Lung function | Estrogen | Progesterone.

Background: Deterioration of lung function is common in women after menopause, which may be related to very low estrogen and progesterone level.Objective: To observe FEF25-75, PEFR and SVC (slow vital capacity) values in apparently healthy postmenopausal women to find out their relationships with serum estrogen and progesterone.Methods: This study was carried out in the Department of Physiology in BSMMU, Dhaka in the year 2007. 30 healthy postmenopausal women aged 45 to 60 years and 30 healthy premenopausal women aged 20 to 30 years during their different phases of menstrual cycle were studied. Postmenopausal women were residents of Dhaka city and premenopausal subjects were medical students. FEF25-75, PEFR and SVC of all subjects were measured by a digital micro spirometer. Their estrogen and progesterone levels were estimated by Micro particle Enzyme Immunoassay (MEIA) method. Data were analyzed by Pearson’s correlation coefficient test, one way ANOVA and unpaired‘t’ testResults: The mean percentage of predicted values of FEF25-75 and PEFR were lower in postmenopausal women compared to those of follicular and luteal phases of premenopausal women but it was not significant. Measured values of SVC was Significantly (p
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