Author(s): Quan HU | Jia-ke CHAI | Hong-ming YANG
Journal: Medical Journal of Chinese People's Liberation Army
ISSN 0577-7402
Volume: 38;
Issue: 5;
Start page: 428;
Date: 2013;
Original page
Keywords: burns | high-energy shock waves | lung injury
ABSTRACT
As a result of military conflict, terrorist attacks, industrial and traffic accidents, the incidence of burn-blast combined injury would be escalating. The burn-blast combined injury was a major clinical problem accompanied by multiple complications and high mortality. The lungs were the most severely injured organ in burn-blast combined injury. Dysfunction of ventilation and gas exchange produced by lung damage could affect oxygen supply to organs and systemic tissues, and is one of the pathophysiological changes resulting in shock and other complications. Previous research has indicated that most of alveolar walls were ruptured, capillaries ruptured, and pulmonary capillary endothelial cells were damaged in the lungs after burn-blast combined injury, and they were followed by pulmonary edema and hemorrhage followed by disorders in ventilation and gas exchange, ending in ischemia and hypoxia of systemic organs. So the treatment of lung injury is the major measure for the treatment of burn-blast combined injury. The pathogenesis and treatment of lung injury in burn-blast combined injury are briefly summarized in this article.
Journal: Medical Journal of Chinese People's Liberation Army
ISSN 0577-7402
Volume: 38;
Issue: 5;
Start page: 428;
Date: 2013;
Original page
Keywords: burns | high-energy shock waves | lung injury
ABSTRACT
As a result of military conflict, terrorist attacks, industrial and traffic accidents, the incidence of burn-blast combined injury would be escalating. The burn-blast combined injury was a major clinical problem accompanied by multiple complications and high mortality. The lungs were the most severely injured organ in burn-blast combined injury. Dysfunction of ventilation and gas exchange produced by lung damage could affect oxygen supply to organs and systemic tissues, and is one of the pathophysiological changes resulting in shock and other complications. Previous research has indicated that most of alveolar walls were ruptured, capillaries ruptured, and pulmonary capillary endothelial cells were damaged in the lungs after burn-blast combined injury, and they were followed by pulmonary edema and hemorrhage followed by disorders in ventilation and gas exchange, ending in ischemia and hypoxia of systemic organs. So the treatment of lung injury is the major measure for the treatment of burn-blast combined injury. The pathogenesis and treatment of lung injury in burn-blast combined injury are briefly summarized in this article.
