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Septal endocarditis, bone infection and severe leg ischemia detected in Tc-99m labelled monoclonal anti granulocyte scan

Author(s): Bechelaghem, A.I. MD. | Habbeche, M. MD. | Benlabgaa, R. MD. | Ghedbane, IE. MD. | Hanzal, A. MD. | Khelifa, A. MD. | Mechcken, F. MD. | Bourezak, SE. MD. | Bouyoucef, SE. MD.

Journal: Alasbimn Journal
ISSN 0717-4055

Volume: 8;
Issue: 33;
Date: 2006;
Original page

Keywords: Bacterial Endocarditis | monoclonal anti granulocyte scintigraphy | leg ischemia | bone infection

Patient 28 years old has continued to have a persistent fever (39.2°C), despite ten days treatment by specific antibiotics for bacterial endocarditis associated to a recent claudication of the right lower leg. The persistent fever has motivated a 99mTc-labelled monoclonal anti granulocyte scan which has showed an important uptake in the myocardial septum, and other infection locations in temporal bone and in right tibial arteries. Two days after, a nanocolloids-99mTc WBS showed no uptake in the heart area, a total absence of uptake of the nanocolloids in the bone marrow of right tibia b and cranial SPECT views confirmed the infectious site in the right temporal bone. New antibiotic strategy was adopted successfully associated with surgical amputation of the right lower leg.
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