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SEROPREVALENCE OF TOXOPLASMA GONDII AMONG SCHIZOPHRENICS AT HOSPITAL KAJANG

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Author(s): Lovetta Yatta Juanah | Juliana Jalaludin | Malina Osman | Zubaidah Jamil Osman

Journal: American Journal of Infectious Diseases
ISSN 1553-6203

Volume: 9;
Issue: 1;
Start page: 11;
Date: 2013;
Original page

Keywords: Toxoplasma Gondii | Schizophrenia | Seroprevalence | Socio-Demographic Risk Factors | Environmental Risk Factors

ABSTRACT
Studies have found a high seroprevalence of T. gondii in schizophrenia patients than controls. This case-control study was done to determine the serprevalence of Toxoplasma gondii and to identify its risk factors among schizophrenia patients at Hospital Kajang. Eighty-eight (88) schizophrenia patients and 88 non-psychiatric controls were examined for the presence of anti-Toxoplasma IgG and IgM antibodies by Enzyme Linked Immunosorbent Assay (ELISA). Questionnaires were used to collect socio-demographic and behavioral data among the respondents. From the results, the seroprevalence of anti-T. gondii IgG antibodies was significantly higher (51.0%) in schizophrenia patients than in controls (30.7%); (OR = 2.01; 95% CI: 2.16-3.01; p = 0.023. There was no significant association between the socio-demographic factors and toxoplasmosis. Beef consumption (p = 0.004, OR = 3.852, CI: 1.550-9.569), pork consumption (p
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