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Significance of segmental glomerulosclerosis in IgA nephropathy: What is the evidence?

Author(s): Mubarak Muhammed | Nasri Hamid

Journal: Journal of Renal Injury Prevention
ISSN 2345-2781

Volume: 2;
Issue: 4;
Start page: 113;
Date: 2013;
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Keywords: IgA nephropathy | Focal segmental glomerulosclerosis | Oxford classification | Columbia classification | Proteinuria | Renal failure

Implication for health policy/practice/research/medical educationPrimary IgA nephropathy (IgAN) is the commonest glomerulopathy worldwide. Its clinical presentation, histology and prognosis vary widely. The lesions of segmental glomerulosclerosis are common in IgAN and represent participation of at least three pathogenetic mechanisms. It is important to identify the different subtypes of segmental sclerosing lesions as these are of prognostic value.
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