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Simulation of thermograph for temperature distribution during kidney perfusion

Author(s): A.A.Dare | E.O.Orodiran

Journal: International Journal of Pharmacy and Biomedical Sciences
ISSN 0976-5263

Volume: 04;
Issue: 01;
Start page: 08;
Date: 2013;
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Keywords: Bioheat | Kidney | Renal perfusion | Renal ischemia | Sub-volume

Heat transfer plays a major role in biological systems because biochemical processes are temperature-dependent. Consequent to poor understanding of temperature history in the kidney, a little success has been recorded during kidney transplant resulting to dysfunction and thermal damage of the vasculature tissue in a number of urological operations. The governing equations were formulated upon the theory of volume average to which the kidney vasculature is treated with respect to the interacting sub-volumes of the tissue sub-volume and the fluid sub-volume of the flowing blood in a continuum perspective. Bio-heat Subroutine of Comsol Multiphysics® was employed in the modeling process. . The result obtained showed temperature profiles at discrete points within the model kidney with a large temperature difference in the fluid sub-volume and tissue-fluid interfaces at BI 0.5 and BI 10.0 indicated the dominance of transient heat convection. Conversely, in the tissue sub-volume, transient heat conduction was observed to be infinitesimally small even at F0 0.2 and F0 2.0 for the discrete points in the model kidney. The model developed in this study finds novel application in monitoring and control of renal temperature during kidney transplant and clinical urology for patients on hemodialysis.
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