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SYNTHESIS OF 2-METHYL-5-NITRO-N-(4-(3-((3-PHENYLQUINOXALIN-2-YL) METHYL) PHENOXY) PHENYL) BENZENESULFONAMIDE AND THEIR ANTIMICROBIAL ACTIVITY Synthese von 2-Methyl-5-NITRO-N-(4 - (3 - ((3-PHENYLQUINOXALIN-2-YL) Methyl) phenoxy) phenyl) BENZENESULFONAMIDE UND IHRE antimikrobielle Aktivität.

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Author(s): RAJARSHI N. PATEL1*, K.B. VYAS2, PIYSH V PATEL3and DINESH S PATEL

Journal: Heterocyclic Letters
ISSN 2231-3087

Volume: 3;
Issue: 3;
Start page: 341;
Date: 2013;
Original page

Keywords: Synthesis | heterocyclic substituted chalcone derivatives | Sulphonamide derivatives | pyrimidin derivatives | antimicrobial activity.

ABSTRACT
Chalcones, precursors of open chain flavonoids and isoflavonoids present in edible plants, and their derivatives have attracted increasing attention due to numerous potential pharmacological applications. They have displayed a broad spectrum of pharmacological activities. Changes in their structure have offered a high degree of diversity that has proven useful for the development of new medicinal agents having improved potency and lesser toxicity. The present review highlights the recently synthesized chalcones and their derivatives possessing important pharmacological activities.

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