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Synthesis and Antibacterial Activity of Urea and Thiourea Derivatives of Anacardic Acid Mixture Isolated from A Natural Product Cashew Nut Shell Liquid (CNSL)

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Author(s): N. Subhakara Reddy | A. Srinivas Rao | M. Adharvana Chari | V. Ravi kumar | V. Jyothy | V. Himabindu

Journal: International Journal of Organic Chemistry
ISSN 2161-4687

Volume: 02;
Issue: 03;
Start page: 267;
Date: 2012;
Original page

Keywords: Synthesis | Urea and Thiourea Derivatives | Anacardic Acid | Anti-Bacterial Activity

ABSTRACT
Synthesis and antibacterial activity of some novel urea and thiourea derivatives (8a - 8k, 9a - 9f) of anacardic acid prepared from commercially available anacardic acid which is obtained from natural product Cashew Nut Shell Liquid (CNSL). Compounds (8a - 8k, 9a - 9f) were tested for Gram positive and Gram negative bacterial cultures. Most of the compounds were showed active compared with standard drug ampicilline.
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