Author(s): Wei Xue | Haichang Li | Huitao Fan | Zhuang Xiong | Yong He | Huixue Qi | Qiujuan Qiu
Journal: Scientific Journal of Frontier Chemical Development
ISSN 2167-163X
Volume: 2;
Issue: 2;
Start page: 43;
Date: 2012;
Original page
Keywords: Bisamide | Benzothiazol | Tobacco mosaic virus | Synthesis
ABSTRACT
Ten novel bisamide compounds containing benzothiazole unit were synthesized from the reactions of substituted benzoic acid and thionyl chloride, then coupled with substituted 2-aminobenzoic acid, cyclized in the existence of acetic anhydride, then coupled with substituted benzo[d]thiazol-2-amine.Their structures were characterized by 1H NMR, 13C NMR, IR and elemental analyses. Preliminary bioassay showed that some compounds exhibited anti-TMV activity at the concentration of 500 μg/mL.
Journal: Scientific Journal of Frontier Chemical Development
ISSN 2167-163X
Volume: 2;
Issue: 2;
Start page: 43;
Date: 2012;
Original page
Keywords: Bisamide | Benzothiazol | Tobacco mosaic virus | Synthesis
ABSTRACT
Ten novel bisamide compounds containing benzothiazole unit were synthesized from the reactions of substituted benzoic acid and thionyl chloride, then coupled with substituted 2-aminobenzoic acid, cyclized in the existence of acetic anhydride, then coupled with substituted benzo[d]thiazol-2-amine.Their structures were characterized by 1H NMR, 13C NMR, IR and elemental analyses. Preliminary bioassay showed that some compounds exhibited anti-TMV activity at the concentration of 500 μg/mL.
