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Synthesis and Biological Evaluation of Novel 6-(3-(4,5-Dihydro-1,5-diphenyl-1H-pyrazol-3-yl)phenylamino) Pyridazin-3(2H)-one Derivatives

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Author(s): Shrikrishna D. Tupare | Satish A. Dake | Santosh V. Nalage | Sidhanath V. Bhosale | Rajita D. Ingle | Rajendra P. Pawar

Journal: International Journal of Organic Chemistry
ISSN 2161-4687

Volume: 02;
Issue: 04;
Start page: 371;
Date: 2012;
Original page

Keywords: Antibacterial Activity | Antifungal Activity | Efficient Synthesis

ABSTRACT
Pyrazoles are important nitrogen containing 5-membered heterocyclic compounds. Numerous pyrazoline derivatives have been found to possess considerable biological activities, which stimulated the research activity in this field. Several 1,3,5-Triphenyl-1H-pyrazole containing 6-aminopyridazin-3(2H)-one derivatives has been synthesized. These new compounds were characterized using IR, 1H-NMR and Mass spectra and Elemental analysis. They possess some potent biological activities. Therefore biological screening of novel compounds has been also done.
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