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Th e infl uence of breast density on the sensitivity and specifi city of ultrasound and mammography in breast cancer diagnosis

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Author(s): Svjetlana Mujagić | Mensura Burina | Hanifa Fejzić

Journal: Acta Medica Academica
ISSN 1840-1848

Volume: 40;
Issue: 2;
Start page: 132;
Date: 2011;
Original page

Keywords: Breast cancer | Breast density | Ultrasound | Mammography

ABSTRACT
Objective. Th e aim of this study was to analyse the sensitivity and specificity of ultrasound and mammography according to breast densityand determine which of these diagnostic imagings is a more accuratetest for diagnosis of breast cancer. Patients and methods. By meansof a cross-sectional study, ultrasound and mammographic examinationsof 148 women with breast disease symptoms were analysed.All women underwent surgery and all lesions were examined by histological examination which revealed the presence of 63 breast cancers,and 85 benign lesions. Histological examination was used as the “goldstandard”. In relation to breast density, the women were separated into two groups, group A: women with “fatty breast” (ACR BI-RADS density categories 1 and 2) and group B: women with “dense breast”(categories 3 and 4). Ultrasound and mammographic findings were classified on the BI-RADS categorical scale of 1-5. For statistical data processing, the logistic regression analysis and the McNemar chi-square test for paired proportions was used. Th e differences on the level of p
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