Author(s): Kamatala Chinna Rajanna | Purugula Venkanna | Mukka Satish Kumar | Soma Ram Gopal
Journal: International Journal of Organic Chemistry
ISSN 2161-4687
Volume: 02;
Issue: 04;
Start page: 336;
Date: 2012;
Original page
Keywords: Vilsmeier Haack (VH) Reagent | Sulfonation | NaHSO3 | Sonication | Aromatic Compounds
ABSTRACT
Sulfonation of aromatic compounds (Phenols, Anilines) is triggered by Vilsmeier Haack (VH) reagent (DMF/POCl3) or (DMF/SOCl2) in the presence of NaHSO3 under Sonication and conventional stirred conditions at room temperature. The reactions afforded corresponding Sulfonic acid derivatives in very good yields. The results obtained under Sonication were enhanced when compared with the yields of the conventional method.
Journal: International Journal of Organic Chemistry
ISSN 2161-4687
Volume: 02;
Issue: 04;
Start page: 336;
Date: 2012;
Original page
Keywords: Vilsmeier Haack (VH) Reagent | Sulfonation | NaHSO3 | Sonication | Aromatic Compounds
ABSTRACT
Sulfonation of aromatic compounds (Phenols, Anilines) is triggered by Vilsmeier Haack (VH) reagent (DMF/POCl3) or (DMF/SOCl2) in the presence of NaHSO3 under Sonication and conventional stirred conditions at room temperature. The reactions afforded corresponding Sulfonic acid derivatives in very good yields. The results obtained under Sonication were enhanced when compared with the yields of the conventional method.
