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In vitro free radical scavenging activity of Sorghum bicolor (L.) Moench

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Author(s): Vijaya1*, N. Sarada mani1 and Varaprasad Bobbarala2

Journal: Drug Invention Today
ISSN 0975-7619

Volume: 2;
Issue: 1;
Start page: 13;
Date: 2010;
Original page

Keywords: Free Radical Scavenging Activity (FRAP) | Sorghum bicolour

ABSTRACT
Sorghum (Sorghum bicolour (L) Monech) is the fifth leading cereal crop in the world and is used primarily in Asia and Africa as food crop. Sorghum is an economically important food crop, it is also used for treatment of several ailments like cardiovascular health, reduce the risk of certain types of cancer and reduce obesity in humans. In the present study, the antioxidant properties of Acetone-water extract from eight genotypes of sorghum were estimated by three different methods. The percentage inhibition of superoxide, hydroxyl and lipid peroxidases were maximum at 100, 300, 1200 µg respectively. The percentage of inhibitions increased with increasing concentrations of extract. Of the eight genotypes, IS-2695 shown maximum of 64.99% inhibition for superoxide radical and the genotype IS-7155 was shown maximum inhibition in hydroxyl, lipid peroxides 67.92% and 82.06% in this order. Significant differences were obtained among the genotypes when the antioxidant activity of the each genotype subjected to a two-way ANOVA.
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