Bright light in elderly subjects with nonseasonal major depressive disorder: a double blind randomised clinical trial using early morning bright blue light comparing dim red light treatment
Author(s): Lieverse Ritsaert | Nielen Marjan | Veltman Dick | Uitdehaag Bernard | van Someren Eus | Smit Jan | Hoogendijk Witte
Volume: 9
Issue: 1
Year: 2008




Community-based randomised controlled trial evaluating falls and osteoporosis risk management strategies
Author(s): Ciaschini PM | Straus SE | Dolovich LR | Goeree RA | Leung KM | Woods CR | Zimmerman GM | Majumdar SR | Spadafora S | Fera LA | Lee HN
Volume: 9
Issue: 1
Year: 2008




Effectiveness of the Austrian disease-management-programme for type 2 diabetes: study protocol of a cluster-randomized controlled trial
Author(s): Sönnichsen Andreas | Rinnerberger Andreas | Url Maria | Winkler Henrike | Kowatsch Peter | Klima Gert | Fürthauer Bernhard | Weitgasser Raimund
Volume: 9
Issue: 1
Year: 2008




A review of RCTs in four medical journals to assess the use of imputation to overcome missing data in quality of life outcomes
Author(s): Fielding Shona | Maclennan Graeme | Cook Jonathan | Ramsay Craig
Volume: 9
Issue: 1
Year: 2008




Protocol for the combined immunosuppression & radiotherapy in thyroid eye disease (CIRTED) trial: A multi-centre, double-masked, factorial randomised controlled trial
Author(s): Rajendram Rathie | Lee Richard | Potts Mike | Rose Geoff | Jain Rajni | Olver Jane | Bremner Fion | Hurel Steven | Cook Anne | Gattamaneni Rao | Tomlinson Marjorie | Plowman Nicholas | Bunce Catey | Hollinghurst Sandra | Kingston Laura | Jackson Sue | Dick Andrew | Rumsey Nichola | Morris Olivia | Dayan Colin | Uddin Jimmy
Volume: 9
Issue: 1
Year: 2008




Randomised controlled trial of thermostatic mixer valves in reducing bath hot tap water temperature in families with young children in social housing: A protocol
Author(s): Kendrick Denise | Stewart Jane | Coupland Carol | Hayes Michael | Hopkins Nick | McCabe Debbie | Murphy Robert | O'Donnell George | Phillips Ceri | Radford David | Ryan Jackie | Smith Sherie | Groom Lindsay | Towner Elizabeth
Volume: 9
Issue: 1
Year: 2008




VAST: Vertebral Artery Stenting Trial. Protocol for a randomised safety and feasibility trial
Author(s): Compter A | van der Worp HB | Schonewille WJ | Vos JA | Algra A | Lo TH | Mali WPThM | Moll FL | Kappelle LJ
Volume: 9
Issue: 1
Year: 2008




Do we want more cancer patients on clinical trials If so, what are the barriers to greater accrual
Author(s): Vickers Andrew
Volume: 9
Issue: 1
Year: 2008




Improving the outcomes of primary care attenders with common mental disorders in developing countries: a cluster randomized controlled trial of a collaborative stepped care intervention in Goa, India
Author(s): Patel Vikram | Kirkwood Betty | Pednekar Sulochana | Araya Ricardo | King Michael | Chisholm Daniel | Simon Gregory | Weiss Helen
Volume: 9
Issue: 1
Year: 2008




Meta-analysis of trials comparing anastrozole and tamoxifen for adjuvant treatment of postmenopausal women with early breast cancer
Author(s): Aydiner Adnan | Tas Faruk
Volume: 9
Issue: 1
Year: 2008




The SU.FOL.OM3 Study: a secondary prevention trial testing the impact of supplementation with folate and B-vitamins and/or Omega-3 PUFA on fatal and non fatal cardiovascular events, design, methods and participants characteristics
Author(s): Galan Pilar | Briancon Serge | Blacher Jacque | Czernichow Sébastien | Hercberg Serge
Volume: 9
Issue: 1
Year: 2008




Design paper: The CapOpus trial: A randomized, parallel-group, observer-blinded clinical trial of specialized addiction treatment versus treatment as usual for young patients with cannabis abuse and psychosis
Author(s): Hjorthøj Carsten | Fohlmann Allan | Larsen Anne-Mette | Madsen Mette | Vesterager Lone | Gluud Christian | Arendt Mikkel | Nordentoft Merete
Volume: 9
Issue: 1
Year: 2008




Effectiveness of computer-tailored Smoking Cessation Advice in Primary Care (ESCAPE): a Randomised Trial
Author(s): Gilbert Hazel | Nazareth Irwin | Sutton Stephen | Morris Richard | Godfrey Christine
Volume: 9
Issue: 1
Year: 2008




Early intervention in panic: randomized controlled trial and cost-effectiveness analysis
Author(s): Meulenbeek Peter | Willemse Godelief | Smit Filip | van Balkom Anton | Spinhoven Philip | Cuijpers Pim
Volume: 9
Issue: 1
Year: 2008




Pearls and perils of an implantable defibrillator trial using a common control: implications for the design of future studies
Author(s): Kudenchuk Peter | Hallstrom Alfred
Volume: 9
Issue: 1
Year: 2008




Protocol of an expertise based randomized trial comparing surgical Venae Sectio versus radiological Puncture of Vena Subclavia for insertion of Totally Implantable Access Port in oncological patients
Author(s): Knebel Philip | Fischer Lars | Cremonese Eva | Lopez-Benitez Ruben | Stampfl Ulrike | Radeleff Boris | Kauczor Hans-Ulrich | Büchler Markus | Seiler Christoph
Volume: 9
Issue: 1
Year: 2008




Clinical and cost-effectiveness of internal limiting membrane peeling for patients with idiopathic full thickness macular hole. Protocol for a Randomised Controlled Trial: FILMS (Full-thickness macular hole and Internal Limiting Membrane peeling Study)
Author(s): Lois Noemi | Burr Jennifer | Norrie John | Vale Luke | Cook Jonathan | McDonald Alison
Volume: 9
Issue: 1
Year: 2008




Inefficacy of different strategies to improve guideline awareness – 5-year follow-up of the hypertension evaluation project (HEP)
Author(s): Hagemeister Jens | Schneider Christian | Diedrichs Holger | Mebus Diana | Pfaff Holger | Wassmer Gernot | Höpp Hans
Volume: 9
Issue: 1
Year: 2008




Review of: Interpreting and Reporting Clinical Trials – A guide to the CONSORT statement and the principles of randomised controlled trials by Anthony Keech, Val Gebski and Rhana Pike
Author(s): Evans Stephen
Volume: 9
Issue: 1
Year: 2008




ZAMSTAR, The Zambia South Africa TB and HIV Reduction study: Design of a 2 × 2 factorial community randomized trial
Author(s): Ayles Helen | Sismanidis Charalambos | Beyers Nulda | Hayes Richard | Godfrey-Faussett Peter
Volume: 9
Issue: 1
Year: 2008




A study to assess changes in myocardial perfusion after treatment with spinal cord stimulation and percutaneous myocardial laser revascularisation; data from a randomised trial
Author(s): Khan Sadia | McNab Duncan | Sharples Linda | Freeman Carol | Hardy Ian | Stone David | Schofield Peter
Volume: 9
Issue: 1
Year: 2008




Reporting of clinical trials: a review of research funders' guidelines
Author(s): Dwan Kerry | Gamble Carrol | Williamson Paula | Altman Douglas
Volume: 9
Issue: 1
Year: 2008




Community-based trial of screening for Chlamydia trachomatis to prevent pelvic inflammatory disease: the POPI (prevention of pelvic infection) trial
Author(s): Oakeshott Pippa | Kerry Sally | Atherton Helen | Aghaizu Adamma | Hay Sima | Taylor-Robinson David | Simms Ian | Hay Phillip
Volume: 9
Issue: 1
Year: 2008




Efficacy of tibolone and raloxifene for the maintenance of skeletal muscle strength, bone mineral density, balance, body composition, cognitive function, mood/depression, anxiety and quality of life/well-being in late postmenopausal women ≥ 70 years: Study design of a randomized, double-blind, double-dummy, placebo-controlled, single-center trial
Author(s): Jacobsen Didy | Samson Monique | Schouw Yvonne | Grobbee Diederick | Verhaar Harald
Volume: 9
Issue: 1
Year: 2008




A randomized double-blind placebo-controlled trial to investigate the effects of nasal calcitonin on bone microarchitecture measured by high-resolution peripheral quantitative computerized tomography in postmenopausal women — Study protocol
Author(s): Richert Laura | Uebelhart Brigitte | Engelhardt Marc | Azria Moise | Rizzoli René
Volume: 9
Issue: 1
Year: 2008




A concept for trial institutions focussing on randomised controlled trials in surgery
Author(s): Rahbari Nuh | Diener Markus | Fischer Lars | Wente Moritz | Kienle Peter | Büchler Markus | Seiler Christoph
Volume: 9
Issue: 1
Year: 2008




The third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke
Author(s): Sandercock Peter | Lindley Richard | Wardlaw Joanna | Dennis Martin | Lewis Steff | Venables Graham | Kobayashi Adam | Czlonkowska Anna | Berge Eivind | Slot Karsten | Murray Veronica | Peeters Andre | Hankey Graeme | Matz Karl | Brainin Michael | Ricci Stefano | Celani Maria | Righetti Enrico | Cantisani Teresa | Gubitz Gord | Phillips Steve | Arauz Antonio | Prasad Kameshwar | Correia Manuel | Lyrer Phillippe
Volume: 9
Issue: 1
Year: 2008




Study Protocol: effects of acupuncture on hot flushes in perimenopausal and postmenopausal women – a multicenter randomized clinical trial
Author(s): Kim Kun-Hyung | Kang Kyung-Won | Jung Hee-Jung | Park Ji-Eun | Jung So-Young | Choi Jun-Yong | Choi Sun-Mi
Volume: 9
Issue: 1
Year: 2008




A randomised, double-masked phase III/IV study of the efficacy and safety of Avastin® (Bevacizumab) intravitreal injections compared to standard therapy in subjects with choroidal neovascularisation secondary to age-related macular degeneration: clinical trial design
Author(s): Patel Praveen | Bunce Catey | Tufail Adnan
Volume: 9
Issue: 1
Year: 2008




Endorsement of the CONSORT Statement by high impact factor medical journals: a survey of journal editors and journal 'Instructions to Authors'
Author(s): Hopewell Sally | Altman Douglas | Moher David | Schulz Kenneth
Volume: 9
Issue: 1
Year: 2008




Prospective controlled randomized trial on prevention of postoperative abdominal adhesions by Icodextrin 4% solution after laparotomic operation for small bowel obstruction caused by adherences [POPA study: Prevention of Postoperative Adhesions on behalf of the World Society of Emergency Surgery]
Author(s): Catena Fausto | Ansaloni Luca | Lauro Augusto | Ercolani Giorgio | D'Alessandro Luigi | Pinna Antonio
Volume: 9
Issue: 1
Year: 2008




Safety of magnetic resonance imaging of patients with a new Medtronic EnRhythm MRI SureScan pacing system: clinical study design
Author(s): Sutton Richard | Kanal Emanuel | Wilkoff Bruce | Bello David | Luechinger Roger | Jenniskens Inge | Hull Michael | Sommer Torsten
Volume: 9
Issue: 1
Year: 2008




Cluster-randomised controlled trial of community mobilisation in Mumbai slums to improve care during pregnancy, delivery, postpartum and for the newborn
Author(s): More Neena | Bapat Ujwala | Das Sushmita | Patil Sarita | Porel Maya | Vaidya Leena | Koriya Bhaveshree | Barnett Sarah | Costello Anthony | Fernandez Armida | Osrin David
Volume: 9
Issue: 1
Year: 2008




Community based trial of home blood pressure monitoring with nurse-led telephone support in patients with stroke or transient ischaemic attack recently discharged from hospital
Author(s): Kerry Sally | Markus Hugh | Khong Teck | Doshi Reena | Conroy Rachel | Oakeshott Pippa
Volume: 9
Issue: 1
Year: 2008




Seminars may increase recruitment to randomised controlled trials: lessons learned from WISDOM
Author(s): Paine Bronwen | Stocks Nigel | MacLennan Alastair
Volume: 9
Issue: 1
Year: 2008




The ACTIVE (Acute Cholecystitis Trial Invasive Versus Endoscopic) study: Multicenter randomized, double-blind, controlled trial of laparoscopic (LC) versus open (LTC) surgery for acute cholecystitis (AC) in adults
Author(s): Catena Fausto | Ansaloni Luca | Di Saverio Salomone | Gazzotti Filippo | Gagliardi Stefano | Coccolini Federico | D'Alessandro Luigi | Ercolani Giorgio | Talarico Carlo | Bassi Uberto | Leone Leonardo | Calzolari Filippo | Pinna Antonio
Volume: 9
Issue: 1
Year: 2008




Automated external cardioversion defibrillation monitoring in cardiac arrest: a randomized trial
Author(s): Ali Bakhtiar | Bloom Heather | Veledar Emir | House Dorothy | Norvel Robert | Dudley Samuel | Zafari A Maziar
Volume: 9
Issue: 1
Year: 2008




Informed consent for clinical trials in acute coronary syndromes and stroke following the European Clinical Trials Directive: investigators' experiences and attitudes
Author(s): Iwanowski Piotr | Budaj Andrzej | Członkowska Anna | Wąsek Wojciech | Kozłowska-Boszko Beata | Olędzka Urszula | Masełbas Wojciech
Volume: 9
Issue: 1
Year: 2008




A pragmatic cluster randomised controlled trial to evaluate the safety, clinical effectiveness, cost effectiveness and satisfaction with point of care testing in a general practice setting – rationale, design and baseline characteristics
Author(s): Laurence Caroline | Gialamas Angela | Yelland Lisa | Bubner Tanya | Ryan Philip | Willson Kristyn | Glastonbury Briony | Gill Janice | Shephard Mark | Beilby Justin
Volume: 9
Issue: 1
Year: 2008




Workflow to improve patient recruitment for clinical trials within hospital information systems – a case-study
Author(s): Dugas Martin | Lange Matthias | Berdel Wolfgang | Müller-Tidow Carsten
Volume: 9
Issue: 1
Year: 2008




Randomized controlled trial to treat migraine with acupuncture: design and protocol
Author(s): Li Ying | Liang Fanrong | Yu Shuguang | Liu Xuguang | Tang Yong | Yang Xuguang | Tian Xiaoping | Yan Jie | Sun Guojie | Chang Xiaorong | Zheng Hui | Zhang Hongxing | Ma Tingting
Volume: 9
Issue: 1
Year: 2008




GENetic and clinical Predictors Of treatment response in Depression: the GenPod randomised trial protocol
Author(s): Thomas Laura | Mulligan Jean | Mason Victoria | Tallon Debbie | Wiles Nicola | Cowen Philip | Nutt David | O'Donovan Michael | Sharp Deborah | Peters Tim | Lewis Glyn
Volume: 9
Issue: 1
Year: 2008




Streamlining tasks and roles to expand treatment and care for HIV: randomised controlled trial protocol
Author(s): Fairall Lara | Bachmann Max | Zwarenstein Merrick | Lombard Carl | Uebel Kerry | van Vuuren Cloete | Steyn Dewald | Boulle Andrew | Bateman Eric
Volume: 9
Issue: 1
Year: 2008




TIPIT: A randomised controlled trial of thyroxine in preterm infants under 28 weeks' gestation
Author(s): Ng Sze | Turner Mark | Gamble Carrol | Didi Mohammed | Victor Suresh | Weindling Alan
Volume: 9
Issue: 1
Year: 2008




GALA: an international multicentre randomised trial comparing general anaesthesia versus local anaesthesia for carotid surgery
Author(s): Gough Michael | Bodenham Andrew | Horrocks Michael | Colam Bridget | Lewis Steff | Rothwell Peter | Banning Adrian | Torgerson David | Gough Moira | Dellagrammaticas Demosthenes | Leigh-Brown Anne | Liapis Christos | Warlow Charles
Volume: 9
Issue: 1
Year: 2008




Design of the Pacemaker REmote Follow-up Evaluation and Review (PREFER) trial to assess the clinical value of the remote pacemaker interrogation in the management of pacemaker patients
Author(s): Chen Jane | Wilkoff Bruce | Choucair Wassim | Cohen Todd | Crossley George | Johnson W Ben | Mongeon Luc | Serwer Gerald | Sherfesee Lou
Volume: 9
Issue: 1
Year: 2008




What constitutes a "clinical trial"?: A survey of oncology professionals
Author(s): Wright James | Kowaleski Brenda | Sussman Jonathan
Volume: 9
Issue: 1
Year: 2008




Investigation of the effect of Interleukin-1 receptor antagonist (IL-1ra) on markers of inflammation in non-ST elevation acute coronary syndromes (The MRC-ILA-HEART Study)
Author(s): Crossman David | Morton Allison | Gunn Julian | Greenwood John | Hall Alistair | Fox Keith | Lucking Andrew | Flather Marcus | Lees Belinda | Foley Claire
Volume: 9
Issue: 1
Year: 2008




Reporting of noninferiority and equivalence randomized trials for major prostaglandins: A systematic survey of the ophthalmology literature
Author(s): Eyawo Oghenowede | Lee Chia-Wen | Rachlis Beth | Mills Edward
Volume: 9
Issue: 1
Year: 2008




Economic evaluation alongside pragmatic randomised trials: developing a standard operating procedure for clinical trials units
Author(s): Edwards Rhiannon | Hounsome Barry | Linck Pat | Russell Ian
Volume: 9
Issue: 1
Year: 2008



