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Molecular Neurodegeneration

ISSN: 1750--1326
Publisher: BioMed Central


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Molecular interplay between leptin, insulin-like growth factor-1, and β-amyloid in organotypic slices from rabbit hippocampus

Author(s): Marwarha Gurdeep | Prasanthi Jaya | Schommer Jared | Dasari Bhanu | Ghribi Othman
Volume: 6
Issue: 1
Year: 2011
Alzheimer's disease: synapses gone cold

Author(s): Koffie Robert | Hyman Bradley | Spires-Jones Tara
Volume: 6
Issue: 1
Year: 2011
Replication of EPHA1 and CD33 associations with late-onset Alzheimer's disease: a multi-centre case-control study

Author(s): Carrasquillo Minerva | Belbin Olivia | Hunter Talisha | Ma Li | Bisceglio Gina | Zou Fanggeng | Crook Julia | Pankratz V | Sando Sigrid | Aasly Jan | Barcikowska Maria | Wszolek Zbigniew | Dickson Dennis | Graff-Radford Neill | Petersen Ronald | Passmore Peter | Morgan Kevin | Younkin Steven
Volume: 6
Issue: 1
Year: 2011
Increased 90-kDa ribosomal S6 kinase (Rsk) activity is protective against mutant huntingtin toxicity

Author(s): Xifró Xavier | Anglada-Huguet Marta | Rué Laura | Saavedra Ana | Pérez-Navarro Esther | Alberch Jordi
Volume: 6
Issue: 1
Year: 2011
Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion protein in vivo

Author(s): Altmeppen Hermann | Prox Johannes | Puig Berta | Kluth Mark | Bernreuther Christian | Thurm Dana | Jorissen Ellen | Petrowitz Bettina | Bartsch Udo | De Strooper Bart | Saftig Paul | Glatzel Markus
Volume: 6
Issue: 1
Year: 2011
Protein S blocks the extrinsic apoptotic cascade in tissue plasminogen activator/N-methyl D-aspartate-treated neurons via Tyro3-Akt-FKHRL1 signaling pathway

Author(s): Guo Huang | Barrett Theresa | Zhong Zhihui | Fernández José | Griffin John | Freeman Robert | Zlokovic Berislav
Volume: 6
Issue: 1
Year: 2011
A mutation in the dynein heavy chain gene compensates for energy deficit of mutant SOD1 mice and increases potentially neuroprotective IGF-1

Author(s): Fergani Anissa | Eschbach Judith | Oudart Hugues | Larmet Yves | Schwalenstocker Birgit | Ludolph Albert | Loeffler Jean-Philippe | Dupuis Luc
Volume: 6
Issue: 1
Year: 2011
Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation

Author(s): Meng Fanjun | Yao Dongdong | Shi Yang | Kabakoff Jonathan | Wu Wei | Reicher Joshua | Ma Yuliang | Moosmann Bernd | Masliah Eliezer | Lipton Stuart | Gu Zezong
Volume: 6
Issue: 1
Year: 2011
Beta-amyloid increases the expression level of ATBF1 responsible for death in cultured cortical neurons

Author(s): Jung Cha-Gyun | Uhm Kyung-Ok | Miura Yutaka | Hosono Takashi | Horike Hirofumi | Khanna Kum | Kim Mi-Jeong | Michikawa Makoto
Volume: 6
Issue: 1
Year: 2011
Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation

Author(s): Davis Richard | Marsden Ian | Maloney Michael | Minamide Laurie | Podlisny Marcia | Selkoe Dennis | Bamburg James
Volume: 6
Issue: 1
Year: 2011
Reduction of mutant huntingtin accumulation and toxicity by lysosomal cathepsins D and B in neurons

Author(s): Liang Qiuli | Ouyang Xiaosen | Schneider Lonnie | Zhang Jianhua
Volume: 6
Issue: 1
Year: 2011
Upregulation of cathepsin D in the caudate nucleus of primates with experimental parkinsonism

Author(s): Yelamanchili Sowmya | Chaudhuri Amrita | Flynn Claudia | Fox Howard
Volume: 6
Issue: 1
Year: 2011
Cu, Zn-superoxide dismutase 1 (SOD1) is a novel target of Puromycin-sensitive aminopeptidase (PSA/NPEPPS): PSA/NPEPPS is a possible modifier of amyotrophic lateral sclerosis

Author(s): Ren Guijie | Ma Zhongcai | Hui Maria | Kudo Lili | Hui Koon-Sea | Karsten Stanislav
Volume: 6
Issue: 1
Year: 2011
Inhibition of RhoA GTPase and the subsequent activation of PTP1B protects cultured hippocampal neurons against amyloid β toxicity

Author(s): Chacon Pedro | Garcia-Mejias Rosa | Rodriguez-Tebar Alfredo
Volume: 6
Issue: 1
Year: 2011
Neuroprotective effect of a new DJ-1-binding compound against neurodegeneration in Parkinson's disease and stroke model rats

Author(s): Kitamura Yoshihisa | Watanabe Shotaro | Taguchi Masanobu | Takagi Kentaro | Kawata Takuya | Takahashi-Niki Kazuko | Yasui Hiroyuki | Maita Hiroshi | Iguchi-Ariga Sanae | Ariga Hiroyoshi
Volume: 6
Issue: 1
Year: 2011
Similarities and differences in structure, expression, and functions of VLDLR and ApoER2

Author(s): Reddy Sunil | Connor Teal | Weeber Edwin | Rebeck William
Volume: 6
Issue: 1
Year: 2011
Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease

Author(s): Jiang Hong | Hampel Harald | Prvulovic David | Wallin Anders | Blennow Kaj | Li Rena | Shen Yong
Volume: 6
Issue: 1
Year: 2011
Tyrosine Phosphorylation of Tau by the Src Family Kinases Lck and Fyn

Author(s): Scales Timothy | Derkinderen Pascal | Leung Kit-Yi | Byers Helen | Ward Malcolm | Price Caroline | Bird Ian | Perera Timothy | Kellie Stuart | Williamson Ritchie | Anderton Brian | Reynolds C Hugh
Volume: 6
Issue: 1
Year: 2011
Impairment of brain endothelial glucose transporter by methamphetamine causes blood-brain barrier dysfunction

Author(s): Abdul Muneer P | Alikunju Saleena | Szlachetka Adam | Murrin L Charles | Haorah James
Volume: 6
Issue: 1
Year: 2011
Lack of neuroprotection in the absence of P2X7 receptors in toxin-induced animal models of Parkinson's disease

Author(s): Hracskó Zsuzsanna | Baranyi Mária | Csölle Cecilia | Gölöncsér Flóra | Madarász Emilia | Kittel Ágnes | Sperlágh Beáta
Volume: 6
Issue: 1
Year: 2011
Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis

Author(s): Zhao Wei | Varghese Merina | Yemul Shrishailam | Pan Yong | Cheng Alice | Marano Paul | Hassan Sadiq | Vempati Prashant | Chen Fei | Qian Xianjuan | Pasinetti Giulio
Volume: 6
Issue: 1
Year: 2011
Microglial phagocytosis induced by fibrillar β-amyloid is attenuated by oligomeric β-amyloid: implications for Alzheimer's disease

Author(s): Pan Xiao-dong | Zhu Yuan-gui | Lin Nan | Zhang Jing | Ye Qin-yong | Huang Hua-pin | Chen Xiao-chun
Volume: 6
Issue: 1
Year: 2011
Preclinical study of dimebon on β-amyloid-mediated neuropathology in Alzheimer's disease

Author(s): Wang Jun | Ferruzzi Mario | Varghese Merina | Qian Xianjuan | Cheng Alice | Xie Mathew | Zhao Wei | Ho Lap | Pasinetti Giulio
Volume: 6
Issue: 1
Year: 2011
Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

Author(s): Lasagna-Reeves Cristian | Castillo-Carranza Diana | Sengupta Urmi | Clos Audra | Jackson George | Kayed Rakez
Volume: 6
Issue: 1
Year: 2011
DJ-1 can inhibit microtubule associated protein 1 B formed aggregates

Author(s): Wang Zhiquan | Zhang Yu | Zhang Shi | Guo Qianqian | Tan Yuyan | Wang Xinyi | Xiong Ran | Ding Jianqing | Chen Shengdi
Volume: 6
Issue: 1
Year: 2011
Transcriptional Regulation of TMP21 by NFAT

Author(s): Liu Shengchun | Zhang Si | Bromley-Brits Kelley | Cai Fang | Zhou Weihui | Xia Kun | Mittelholtz Jill | Song Weihong
Volume: 6
Issue: 1
Year: 2011
Pleiotrophin over-expression provides trophic support to dopaminergic neurons in parkinsonian rats

Author(s): Taravini Irene | Chertoff Mariela | Cafferata Eduardo | Courty José | Murer Mario | Pitossi Fernando | Gershanik Oscar
Volume: 6
Issue: 1
Year: 2011
A new role for interferon gamma in neural stem/precursor cell dysregulation

Author(s): Walter Janine | Honsek Silke | Illes Sebastian | Wellen Jennifer | Hartung Hans-Peter | Rose Christine | Dihné Marcel
Volume: 6
Issue: 1
Year: 2011
Decreased expression of B cell related genes in leukocytes of women with Parkinson's disease

Author(s): Kedmi Merav | Bar-Shira Anat | Gurevich Tanya | Giladi Nir | Orr-Urtreger Avi
Volume: 6
Issue: 1
Year: 2011
T cell mediated cerebral hemorrhages and microhemorrhages during passive Aβ immunization in APPPS1 transgenic mice

Author(s): Meyer-Luehmann Melanie | Mora J Rodrigo | Mielke Matthew | Spires-Jones Tara | de Calignon Alix | von Andrian Ulrich | Hyman Bradley
Volume: 6
Issue: 1
Year: 2011
Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

Author(s): Woodruff Trent | Thundyil John | Tang Sung-Chun | Sobey Christopher | Taylor Stephen | Arumugam Thiruma
Volume: 6
Issue: 1
Year: 2011
Gene expression endophenotypes: a novel approach for gene discovery in Alzheimer's disease

Author(s): Ertekin-Taner Nilüfer
Volume: 6
Issue: 1
Year: 2011
Mutant Prpf31 causes pre-mRNA splicing defects and rod photoreceptor cell degeneration in a zebrafish model for Retinitis pigmentosa

Author(s): Yin Jun | Brocher Jan | Fischer Utz | Winkler Christoph
Volume: 6
Issue: 1
Year: 2011
Alzheimer-specific variants in the 3'UTR of Amyloid precursor protein affect microRNA function

Author(s): Delay Charlotte | Calon Frédéric | Mathews Paul | Hébert Sébastien
Volume: 6
Issue: 1
Year: 2011
A glycine zipper motif mediates the formation of toxic β-amyloid oligomers in vitro and in vivo

Author(s): Fonte Virginia | Dostal Vishantie | Roberts Christine | Gonzales Patrick | Lacor Pascale | Magrane Jordi | Dingwell Natalie | Fan Emily | Silverman Michael | Stein Gretchen | Link Christopher
Volume: 6
Issue: 1
Year: 2011
Downregulation of CREB expression in Alzheimer's brain and in Aβ-treated rat hippocampal neurons

Author(s): Pugazhenthi Subbiah | Wang Maorong | Pham Serena | Sze Chun-I | Eckman Christopher
Volume: 6
Issue: 1
Year: 2011
Bovine spongiform encephalopathy infection alters endogenous retrovirus expression in distinct brain regions of cynomolgus macaques (Macaca fascicularis)

Author(s): Greenwood Alex | Vincendeau Michelle | Schmädicke Ann-Christin | Montag Judith | Seifarth Wolfgang | Motzkus Dirk
Volume: 6
Issue: 1
Year: 2011
TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6

Author(s): Fiesel Fabienne | Schurr Christine | Weber Stephanie | Kahle Philipp
Volume: 6
Issue: 1
Year: 2011
Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction

Author(s): Giralt Albert | Carretón Olga | Lao-Peregrin Cristina | Martín Eduardo | Alberch Jordi
Volume: 6
Issue: 1
Year: 2011
Protein kinase D1 (PKD1) activation mediates a compensatory protective response during early stages of oxidative stress-induced neuronal degeneration

Author(s): Asaithambi Arunkumar | Kanthasamy Arthi | Saminathan Hariharan | Anantharam Vellareddy | Kanthasamy Anumantha
Volume: 6
Issue: 1
Year: 2011
Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold

Author(s): Grabrucker Andreas | Schmeisser Michael | Udvardi Patrick | Arons Magali | Schoen Michael | Woodling Nathaniel | Andreasson Katrin | Hof Patrick | Buxbaum Joseph | Garner Craig | Boeckers Tobias
Volume: 6
Issue: 1
Year: 2011
6-OHDA generated ROS induces DNA damage and p53- and PUMA-dependent cell death

Author(s): Bernstein Alison | Garrison Sean | Zambetti Gerard | O'Malley Karen
Volume: 6
Issue: 1
Year: 2011
A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection

Author(s): L'Episcopo Francesca | Serapide Maria | Tirolo Cataldo | Testa Nunzio | Caniglia Salvatore | Morale Maria | Pluchino Stefano | Marchetti Bianca
Volume: 6
Issue: 1
Year: 2011
Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse

Author(s): Takamura Ayumi | Okamoto Yasuhide | Kawarabayashi Takeshi | Yokoseki Tatsuki | Shibata Masao | Mouri Akihiro | Nabeshima Toshitaka | Sun Hui | Abe Koji | Urisu Tsuneo | Yamamoto Naoki | Shoji Mikio | Yanagisawa Katsuhiko | Michikawa Makoto | Matsubara Etsuro
Volume: 6
Issue: 1
Year: 2011
Differential regulation of BACE1 expression by oxidative and nitrosative signals

Author(s): Kwak Young-Don | Wang Ruishan | Li Jing | Zhang Yun-Wu | Xu Huaxi | Liao Francesca-Fang
Volume: 6
Issue: 1
Year: 2011
Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neurons

Author(s): Lambert Wendi | Ruiz Lupe | Crish Samuel | Wheeler Larry | Calkins David
Volume: 6
Issue: 1
Year: 2011
Disruption of the NF-κB/IκBα Autoinhibitory Loop Improves Cognitive Performance and Promotes Hyperexcitability of Hippocampal Neurons

Author(s): Shim David | Yang Li | Reed J | Noebels Jeffrey | Chiao Paul | Zheng Hui
Volume: 6
Issue: 1
Year: 2011
Glutathione Peroxidase 4 is associated with Neuromelanin in Substantia Nigra and Dystrophic Axons in Putamen of Parkinson's brain

Author(s): Bellinger Frederick | Bellinger Miyoko | Seale Lucia | Takemoto Andrea | Raman Arjun | Miki Takanori | Manning-Boğ Amy | Berry Marla | White Lon | Ross G
Volume: 6
Issue: 1
Year: 2011
Selective inhibition of GluN2D-containing N-methyl-D-aspartate receptors prevents tissue plasminogen activator-promoted neurotoxicity both in vitro and in vivo

Author(s): Jullienne Amandine | Montagne Axel | Orset Cyrille | Lesept Flavie | Jane David | Monaghan Daniel | Maubert Eric | Vivien Denis | Ali Carine
Volume: 6
Issue: 1
Year: 2011

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