Activation of K-RAS by co-mutation of codons 19 and 20 is transforming
Author(s): Naguib Adam | Wilson Catherine | Adams David | Arends Mark
Volume: 6
Issue: 1
Year: 2011




Combination of dasatinib and curcumin eliminates chemo-resistant colon cancer cells
Author(s): Nautiyal Jyoti | Kanwar Shailender | Yu Yingjie | Majumdar Adhip
Volume: 6
Issue: 1
Year: 2011




AKAP5 and AKAP12 Form Homo-oligomers
Author(s): Gao Shujuan | Wang Hsien-yu | Malbon Craig
Volume: 6
Issue: 1
Year: 2011




Distinct roles of MK2 and MK5 in cAMP/PKA- and stress/p38MAPK-induced heat shock protein 27 phosphorylation
Author(s): Shiryaev Alexey | Dumitriu Gianina | Moens Ugo
Volume: 6
Issue: 1
Year: 2011




Canonical Wnt signaling is involved in switching from cell proliferation to myogenic differentiation of mouse myoblast cells
Author(s): Tanaka Shingo | Terada Kumiko | Nohno Tsutomu
Volume: 6
Issue: 1
Year: 2011




E4BP4 facilitates glucocorticoid-evoked apoptosis of human leukemic CEM cells via upregulation of Bim
Author(s): Beach Jessica | Nary Laura | Hirakawa Yasuko | Holland Eli | Hovanessian Rebeka | Medh Rheem
Volume: 6
Issue: 1
Year: 2011




Characterization of the Rac guanine nucleotide exchange factor P-Rex1 in platelets
Author(s): Aslan Joseph | Spencer Alex | Loren Cassandra | Pang Jiaqing | Welch Heidi | Greenberg Daniel | McCarty Owen
Volume: 6
Issue: 1
Year: 2011




AKAP12 and AKAP5 form higher-order hetero-oligomers
Author(s): Gao Shujuan | Wang Hsien-yu | Malbon Craig
Volume: 6
Issue: 1
Year: 2011




Probing the physical nature and composition of signalsomes
Author(s): Wang Hsien-yu | Malbon Craig
Volume: 6
Issue: 1
Year: 2011




G-patch domain and KOW motifs-containing protein, GPKOW; a nuclear RNA-binding protein regulated by protein kinase A
Author(s): Aksaas Anne | Larsen Anja | Rogne Marie | Rosendal Ken | Kvissel Anne-Katrine | Skålhegg Bjørn
Volume: 6
Issue: 1
Year: 2011




Dual function of polycomb group proteins in differentiated murine T helper (CD4+) cells
Author(s): Jacob Eyal | Hod-Dvorai Reut | Ben-Mordechai Or | Boyko Yulia | Avni Orly
Volume: 6
Issue: 1
Year: 2011




Rad6B acts downstream of Wnt signaling to stabilize β-catenin: Implications for a novel Wnt/β-catenin target
Author(s): Gerard Brigitte | Tait Larry | Nangia-Makker Pratima | Shekhar Malathy
Volume: 6
Issue: 1
Year: 2011




AKAR2-AKAP12 fusion protein "biosenses" dynamic phosphorylation and localization of a GPCR-based scaffold
Author(s): Tao Jiangchuan | Wang Hsien-yu | Malbon Craig
Volume: 5
Issue: 1
Year: 2010




Adenoviral oncoprotein E1B55K mediates colocalization of SSBP2 and PML in response to stress
Author(s): Fleisig Helen | Liang Hong | Nagarajan Lalitha
Volume: 5
Issue: 1
Year: 2010




Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer
Author(s): Roy Sanjit | Srivastava Rakesh | Shankar Sharmila
Volume: 5
Issue: 1
Year: 2010




Dishevelled-3 C-terminal His single amino acid repeats are obligate for Wnt5a activation of non-canonical signaling
Author(s): Ma Li | Wang Ying | Malbon Craig | Wang Hsien-yu
Volume: 5
Issue: 1
Year: 2010




Chaperones contribute to G protein coupled receptor oligomerization, but do not participate in assembly of the G protein with the receptor signaling complex
Author(s): Hammad Maha | Dupré Denis
Volume: 5
Issue: 1
Year: 2010




EGFR/Met association regulates EGFR TKI resistance in breast cancer
Author(s): Mueller Kelly | Yang Zeng-Quan | Haddad Ramsi | Ethier Stephen | Boerner Julie
Volume: 5
Issue: 1
Year: 2010




TLN-4601 suppresses growth and induces apoptosis of pancreatic carcinoma cells through inhibition of Ras-ERK MAPK signaling
Author(s): Campbell Paul | Boufaied Nadia | Fiordalisi James | Cox Adrienne | Falardeau Pierre | Der Channing | Gourdeau Henriette
Volume: 5
Issue: 1
Year: 2010




Genetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cells
Author(s): González-Pérez Vanessa | Reiner David | Alan Jamie | Mitchell Cicely | Edwards Lloyd | Khazak Vladimir | Der Channing | Cox Adrienne
Volume: 5
Issue: 1
Year: 2010




NSC109268 potentiates cisplatin-induced cell death in a p53-independent manner
Author(s): Shankar Eswar | Basu Chandreyi | Adkins Brett | Siede Wolfram | Basu Alakananda
Volume: 5
Issue: 1
Year: 2010




AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in acute lymphoblastic leukemia
Author(s): Leclerc Gilles | Leclerc Guy | Fu Guilian | Barredo Julio
Volume: 5
Issue: 1
Year: 2010




AMPK exerts dual regulatory effects on the PI3K pathway
Author(s): Tao Rong | Gong Jun | Luo Xixi | Zang Mengwei | Guo Wen | Wen Rong | Luo Zhijun
Volume: 5
Issue: 1
Year: 2010




Glycogen Synthase Kinase-3beta regulates Snail and beta-catenin during gastrin-induced migration of gastric cancer cells
Author(s): Mishra Prajna | Senthivinayagam Subramanian | Rana Ajay | Rana Basabi
Volume: 5
Issue: 1
Year: 2010




Peroxisome proliferator-activated receptor gamma ligand-mediated apoptosis of hepatocellular carcinoma cells depends upon modulation of PI3Kinase pathway independent of Akt
Author(s): Mishra Prajna | Paramasivam Suresh | Thylur Ramesh | Rana Ajay | Rana Basabi
Volume: 5
Issue: 1
Year: 2010




The adaptor protein SH2B1β reduces hydrogen peroxide-induced cell death in PC12 cells and hippocampal neurons
Author(s): Lu Wan-Chen | Chen Chien-Jen | Hsu Hui-Chien | Hsu Hsin-Ling | Chen Linyi
Volume: 5
Issue: 1
Year: 2010




Zinc release from thapsigargin/IP3-sensitive stores in cultured cortical neurons
Author(s): Stork Christian | Li Yang
Volume: 5
Issue: 1
Year: 2010




Transformation by a nucleotide-activated P2Y receptor is mediated by activation of Gαi, Gαq and Rho-dependent signaling pathways
Author(s): Singh Anurag | Boyer José | Der Channing | Zohn Irene
Volume: 5
Issue: 1
Year: 2010




A novel mechanism of cell growth regulation by Cell Cycle and Apoptosis Regulatory Protein (CARP)-1
Author(s): Jiang Yan | Puliyappadamba Vineshkumar | Zhang Liyue | Wu Wenjuan | Wali Anil | Yaffe Michael | Fontana Joseph | Rishi Arun
Volume: 5
Issue: 1
Year: 2010




Expression analyses of nuclear receptor genes in breast cancer cell lines exposed to soy phytoestrogens after BRCA2 knockdown by TaqMan Low-Density Array (TLDA)
Author(s): Satih Samir | Savinel Hélène | Rabiau Nadège | Fontana Luc | Bignon Yves-Jean | Bernard-Gallon Dominique
Volume: 4
Issue: 1
Year: 2009




Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis
Author(s): Hirakawa Yasuko | Nary Laura | Medh Rheem
Volume: 4
Issue: 1
Year: 2009




Romidepsin inhibits Ras-dependent growth transformation of NIH 3T3 fibroblasts and RIE-1 epithelial cells independently of Ras signaling inhibition
Author(s): Hanker Ariella | Healy Kevin | Nichols Jean | Der Channing
Volume: 4
Issue: 1
Year: 2009




AKT/eNOS signaling module functions as a potential feedback loop in the growth hormone signaling pathway
Author(s): Li Cong-Jun | Elsasser Theodore | Kahl Stanislaw
Volume: 4
Issue: 1
Year: 2009




Immature and mature species of the human Prostacyclin Receptor are ubiquitinated and targeted to the 26S proteasomal or lysosomal degradation pathways, respectively
Author(s): Donnellan Peter | Kinsella B Therese
Volume: 4
Issue: 1
Year: 2009




Membrane estrogen receptor-α-mediated nongenomic actions of phytoestrogens in GH3/B6/F10 pituitary tumor cells
Author(s): Jeng Yow-Jiun | Kochukov Mikhail | Watson Cheryl
Volume: 4
Issue: 1
Year: 2009




Overexpression of tissue inhibitors of metalloproteinase 2 up-regulates NF-κB activity in melanoma cells
Author(s): Sun Jun | Stetler-Stevenson William
Volume: 4
Issue: 1
Year: 2009




Molecular mechanism of regulation of OGG1: tuberin deficiency results in cytoplasmic redistribution of transcriptional factor NF-YA
Author(s): Habib Samy
Volume: 4
Issue: 1
Year: 2009




Cell cycle arrest in Metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27Kip1 or p21Cip1
Author(s): Zhuang Yongxian | Miskimins W Keith
Volume: 3
Issue: 1
Year: 2008




CK2beta gene silencing increases cell susceptibility to influenza A virus infection resulting in accelerated virus entry and higher viral protein content
Author(s): Marjuki Henju | Scholtissek Christoph | Yen Hui-Ling | Webster Robert
Volume: 3
Issue: 1
Year: 2008




Differential role of beta-arrestin ubiquitination in agonist-promoted down-regulation of M1 vs M2 muscarinic acetylcholine receptors
Author(s): Mosser Valerie | Jones Kymry | Hoffman Katie | McCarty Nael | Jackson Darrell
Volume: 3
Issue: 1
Year: 2008




Data-driven modeling of cellular stimulation, signaling and output response in RAW 264.7 cells
Author(s): Wu Yang | Johnson Gary | Gomez Shawn
Volume: 3
Issue: 1
Year: 2008




Enhanced catharanthine and vindoline production in suspension cultures of Catharanthus roseus by ultraviolet-B light
Author(s): Ramani Shilpa | Jayabaskaran Chelliah
Volume: 3
Issue: 1
Year: 2008




SFRP-4 abrogates Wnt-3a-induced β-catenin and Akt/PKB signalling and reverses a Wnt-3a-imposed inhibition of in vitro mammary differentiation
Author(s): Constantinou Thecla | Baumann Fabrizio | Lacher Markus | Saurer Susanne | Friis Robert | Dharmarajan Arun
Volume: 3
Issue: 1
Year: 2008




The α1D-adrenergic receptor is expressed intracellularly and coupled to increases in intracellular calcium and reactive oxygen species in human aortic smooth muscle cells
Author(s): García-Cazarín Mary | Smith Jennifer | Olszewski Kyle | McCune Dan | Simmerman Linda | Hadley Robert | Kraner Susan | Piascik Michael
Volume: 3
Issue: 1
Year: 2008




Association of TRAF2 with the short form of cellular FLICE-like inhibitory protein prevents TNFR1-mediated apoptosis
Author(s): Kim Dong-Joon | Park Chan | Oh Bermseok | Kim Young-Youl
Volume: 3
Issue: 1
Year: 2008




Dramatic inhibition of osteoclast sealing ring formation and bone resorption in vitro by a WASP-peptide containing pTyr294 amino acid
Author(s): Ma Tao | Samanna Venkatesababa | Chellaiah Meenakshi
Volume: 3
Issue: 1
Year: 2008




Mutations on the Switch III region and the alpha3 helix of Galpha16 differentially affect receptor coupling and regulation of downstream effectors
Author(s): Yu May | Ho Maurice | Liu Andrew | Wong Yung
Volume: 3
Issue: 1
Year: 2008




G-protein-coupled receptor-associated A-kinase anchoring proteins AKAP5 and AKAP12: differential signaling to MAPK and GPCR recycling
Author(s): Tao Jiangchuan | Malbon Craig
Volume: 3
Issue: 1
Year: 2008




Inhibition of PI3K/AKT and MEK/ERK pathways act synergistically to enhance antiangiogenic effects of EGCG through activation of FOXO transcription factor
Author(s): Shankar Sharmila | Chen Qinghe | Srivastava Rakesh
Volume: 3
Issue: 1
Year: 2008




The neurotransmitter dopamine modulates vascular permeability in the endothelium
Author(s): Bhattacharya Resham | Sinha Sutapa | Yang Su-Ping | Patra Chittaranjan | Dutta Shamit | Wang Enfeng | Mukhopadhyay Debabrata
Volume: 3
Issue: 1
Year: 2008



